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hematology syndromes anemia aplastic apml cancer cardiology classification differentiation dress encephalopathy endocarditis hodgkins immune inflammatory iris leukemia lymphoma mds myelodysplasia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... : >3 symptoms, or ... Diagnosis: Infection ... #management #hematology ... #oncology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Resolution > 15 days Differentials ... • SJS/TEN • Acute ... : symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
confirm DAH, r/o infection ... or serologies + symptoms ... #differential # ... diagnosis #management ... #treatment
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... extramedullary disease ... -> AML: Blast crises ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
(PRES) Overview ... Shock, Autoimmune disease ... Neurological symptoms ... Reversible course Differential ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... and petechiae Causes ... • Improve the symptoms ... #hematology #diagnosis ... #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... with systemic disease ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... - Overview of IRIS ... worsening of that disease ... #Differential # ... Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... Culture Positive: • Acute ... Cerebral > Splenic, Pulmonary ... Cholesterol emboli syndrome ... #infectiousdiseases
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