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oncology causes thrombocytosis allergy cardiology cll dermatology endocarditis erythematosus gravis immunology lupus lymphocytic management mds myasthenia myelodysplasia myelodysplastic neurology pathergy
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelogenous Leukemia ... Myelofibrosis Infectious ... • Celiac disease ... #Diagnosis #Algorithm
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Arthritis • SLE ... Fatigue Syndrome ... #Chronic #Fatigue ... Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... for workup, including ... Rebound effect from treatment ... : Chronic infections ... #Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Chronic leukemia ... extramedullary disease ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... sweats • Extreme fatigue ... cells can indicate disease ... #diagnosis #workup ... #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Clinical evidence of (fatigue ... permanent alopecia Differential ... fibromyalgia) • Infections ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis Overview ... an autoimmune disorder ... rheumatoid arthritis, SLE ... - Generalized fatigue ... inhibition - Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... Marrow Failure • Chronic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Endocarditis - Overview ... • Autoimmune (SLE ... fever, Malaise, fatigue ... Cholesterol emboli syndrome ... #infectiousdiseases
Pathergy Summary Overview What is pathergy? Pathergy is an exaggerated skin injury occurring after minor trauma such as
Pathergy Summary Overview ... following: • Behcet Disease ... • Chronic myeloid ... leukemia (CML) ... #differential #
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