14 results
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Escalation in Potency: Clopidogrel ... to Prasugrel, Clopidogrel ... : Prasugrel to Clopidogrel ... Ticagrelor to Clopidogrel ... switching #conversion #Clopidogrel
Oral P2Y12 Inhibitor Pharmacology

 • Clopidogrel
 • Prasugrel
 • Ticagrelor

By Kyle Fischer, PharmD @Kfischer_10

#P2Y12 #Inhibitor #Pharmacology
Oral P2Y12 Inhibitor ... Pharmacology • Clopidogrel ... Kfischer_10 #P2Y12 ... table #plavix #clopidogrel
Antiplatelet Conversion - P2Y12 Inhibitor Switching
 • Clopidogrel (Plavix)
 • Prasugrel (Effient)
 • Ticagrelor (Brilinta)
Clopidogrel and
Antiplatelet Conversion - P2Y12 ... Inhibitor Switching • Clopidogrel ... active site of the P2Y12 ... the binding of clopidogrel ... Antiplatelet #Conversion #P2Y12
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
Clopidogrel (Plavix ... ) and Clopidogrel ... Non-responders Clopidogrel ... diphosphate receptor: P2Y12 ... Clopidogrel
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 ... anticoagulation in a-fib P2Y12 ... Inhibitors (clopidogrel ... - Inhibits the P2Y12
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors
A, Switching between oral agents in the acute/early phase.
Switching Between Oral P2Y12 ... of the previous clopidogrel ... de-escalation with clopidogrel ... ticagrelor to clopidogrel ... CIRCULATIONAHA.117.031164 #P2Y12
Trends in Platelet Adenosine Diphosphate P2Y12 Receptor Inhibitor Use and Adherence Among Antiplatelet-Naive Patients After Percutaneous
Adenosine Diphosphate P2Y12 ... #ADPInhibitor #Clopidogrel
Cangrelor - Pharmacology
Cangrelor (Kengreal) is a parenteral analogue of adenosine triphosphate
Cangrelor binds reversibly to the platelet
to the platelet P2Y12 ... pre-treated with an oral P2Y12 ... prasugrel and clopidogrel ... if the platelet P2Y12 ... the effects of clopidogrel
Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor
with aspirin and clopidogrel ... antiplatelet therapy with clopidogrel ... Management #Aspirin #Clopidogrel
The 8 A’s — drugs that interact with warfarin
Antibiotics 
 - Most agents, but especially co-trimoxazole,
Acetylsalicylic acid, clopidogrel