9 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... common • Imaging: CXR ... sepsis), PE, DAH, CHF ... #management #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... • Serotonin syndrome ... Checklist #Diagnosis #Management ... #Workup
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
remember to tailor treatment ... obtain 12-lead ECG ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... • Visual inspection ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup #Cardiology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
indicated, start CPR ... thoracotomy is a better treatment ... examination and vital signs ... Plan definitive management ... #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... antibody that works ... • CSF: Oligoclonal ... Treatment: • ... #treatment #neurology
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
of more of the signs ... arrest, start CPR ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management ... #Workup
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment ... #heartfailure #chf
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... full infectious work-up ... days → add fungal work-up ... interventional radiology ... (~20 %) and APL