9 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... response preceding infection ... Treatment: • Plasmapheresis ... #diagnosis #management ... #treatment #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
, dyspnea, +/- CXR ... WBC >100k, + lab signs ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Serologic and EMG ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... and cauda equina TREATMENT ... SinaiBmoreIMRes #GBS #Guillain ... #Barre #Syndrome ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... common • Imaging: CXR ... APML #diagnosis #management
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
failure with Reduced Ejection ... of CXR congestion ... Jcortesizaguirr #HFrEF #heartfailure ... #diagnosis #management ... #cardiology #pharmacology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment ... table #foamed #heartfailure
Spontaneous Bacterial Peritonitis
DIAGNOSTICS
Paracentesis: 
 • Calculate absolute PMN count (total WBC x PMN %)
 • Correct
Treat if other signs ... 1: 1.5 g/kg of ... ↓ rebleeding, infections ... SBP #diagnosis #management ... #prophylaxis #treatment
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... search for and treatment ... Presentation • Common Signs ... Treatment Approach