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diagnosis differential disease hematology vasculitis algorithm dermatology giantcell neurology 2ndline acr2021 activation adult antinxp2 antinxp2dm aosd apml arthritis bacterial calcium
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... disease, Vasculitis (e.g ... ., PAN) • Seizures ... Cardiomyopathies - Viral infection ... differential #diagnosis #rheumatology
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... cell arteritis ... #GCA #Treatment ... #Management #Relapses ... #Indications #rheumatology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
) - Vasculitis Management ... immunosuppressive agent (e.g ... Nodosa #Vasculitis #Management ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... systemic sx + signs ... Treatment of GCA ... them, but urgent rheumatology ... #Diagnosis #Management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Pathways: - 1. ... arthralgia, and arthritis ... tissue disorder (e.g ... SLE), rheumatoid arthritis ... classification #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
, rheumatoid arthritis ... weakness in: 1. ... Findings: 1. ... - Peek sign ... Gravis #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as IL-1 ... juvenile idiopathic arthritis ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... AM stiffness, >1 ... corticosteroid injections ... #diagnosis #management ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... Elevated ESR and CRP GCA ... develop in pts with GCA ... Polyarteritis Nodosa: • PAN ... Differential #Diagnosis #Rheumatology
Systemic Inflammatory Response Syndrome (SIRS) • Non-specific (infections vs non-infectious) • ≥2 of the following: o Temp >38°C or <36°C o HR >90 bpm o RR
Inflammatory Response Syndrome ... mental status (GCS ... >2 mmol/L Management ... recognition & treatment ... (within 1 hour)
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