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diagnosis rheumatology hemophagocytic hlh lymphohistiocytosis treatment activation algorithm antinxp2 antinxp2dm apml blood chf clinical criticalcare dermatomyositis differential differentiation foamed heartfailure
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... WBC >100k, + lab signs ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... underlying disease (eg ... SLE], AOSD) • Infection ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... Diagnosis: HLH signs ... can mimic common infections ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
antiinflammatory properties e.g ... TNF blockers had ... #Rheumatology # ... diagnosis #management ... #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Prednisone 5mg/kg ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... JVD, Orthopnea/PND ... acute coronary syndrome ... differential #algorithm #management ... #cardiology #treatment
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... of patients who had ... FNHTR once had ... Transfusions #diagnosis #management ... #hematology #reactions
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... patients with the HLH syndrome ... Presentation • Common Signs ... #Hematology #HemeOnc
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... antibody positive had ... Prednisone at 1 mg/kg ... Dermatomyositis #diagnosis #management ... dermatology
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