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management differential neurology activetb algorithm causes hematology latenttb radiology brain criticalcare idsa infectiousdiseases pharmacology pulmonary 1 a4c abscess active anemia
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infections/year ... for 4.6% of new infections ... HIV • Recent infection ... inhibitors • Injection ... #TB #Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infections/year ... for 4.6% of new infections ... HIV • Recent infection ... inhibitors • Injection ... #TB #Diagnosis
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
developing active infection ... infection • Recent ... viral infections ... Extrapulmonary infection ... #Workup #TB #Latent
Pulmonary Tuberculosis - Patterns of Involvement • Scarring, Nodules and Consolidation - Lobar
Pulmonary Tuberculosis ... spread of MTB infection ... #TB #Patterns # ... chest #xray #clinical ... #radiology #CXR
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
straw-colored yellow, infection ... culture bottles (infection ... concentration (malignancy, infection ... LDH (malignancy, infection ... Jcortesizaguirr #Ascites #workup
Tuberculin Skin Test Interpretation - Threshold for treatment Induration cutoff >5mm: • Recent exposure to an individual
Threshold for treatment ... consistent with old TB ... Underweight • Injection ... individuals #Tuberculosis ... SkinTest #TST #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... TPO, TPO-RA • Infections ... : Chronic infections ... , TB, Acute bacterial ... and viral infections
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
skin lesions, LAD ... splenomegaly Other infections ... including: M, avium, TB ... Bacterial • Tuberculosis ... #causes #radiology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... organ-specific signs ... #Differential #diagnosis
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Mycobacterium Tuberculosis ... Infection and Disease ... and molecular diagnostic ... HIV-infected persons with clinical ... opportunistic #infections
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