24 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... sepsis), PE, DAH, CHF ... #oncology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... CNS #neurology #rheumatology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Clinical Manifestations ... : • Anti-GAD Ab ... • CSF: Oligoclonal ... Treatment: • ... Diagnosis #Management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
brain PRES Clinical ... PRES-Associated Clinical ... • EEG: With persistent ... epilepticus Treatment ... underlying cause • Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... Idiopathic • Infections ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of congestion ... JVD, Orthopnea/PND ... acute coronary syndrome ... algorithm #management #cardiology ... #heartfailure #chf