14 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
infections (bacterial ... ), RA, crystal disease ... tumor • Non-bloody ... that patient had ... #rheumatology #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hematologic: Acute blood ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... , TB, Acute bacterial
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Fever • Bacterial ... , Vasculitis (e.g ... ., PAN) • Seizures ... arteritis • Bloody ... differential #diagnosis #rheumatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... Blood products contain ... very rare), or bacterial ... - Bacterial
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... > Inability to produce ... plasma cells in blood ... infections (e.g
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood products contain ... very rare), or bacterial ... • Bacterial contamination ... RBCs (stored at 4C ... diagnosis #management #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... which can plug blood ... • Fibrin split products ... Atherosclerotic PVD ... Cryofibrinogenemia #diagnosis #rheumatology
Spontaneous Bacterial Peritonitis
DIAGNOSTICS
Paracentesis: 
 • Calculate absolute PMN count (total WBC x PMN %)
 • Correct
ascitic fluid in blood ... Treat if other signs ... ↓ rebleeding, infections ... advanced liver disease ... #prophylaxis #treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... • Major blood ... muscle aches, joint ... dissemination occurs and produces ... have positive blood
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... vesicular eruption • Joints ... Palpable purpura, joint ... Differential #Diagnosis #Rheumatology