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diagnosis management differential algorithm blood reactions vasculitis acr2021 activation antinxp2 antinxp2dm conditions cryofibrinogenemia dermatology dermatomyositis extrarticular guidelines joint macrophage mas
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... , TB, Acute bacterial ... Diagnosis #Algorithm #hematology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Severe Disease → Remission
Guidelines • Severe Disease ... • Non-Severe Disease ... immunosuppressive agent (e.g ... Vasculitis #Management #Treatment ... Guidelines #algorithm #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... • Fibrin split products ... Atherosclerotic PVD ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... very rare), or bacterial ... - Bacterial ... RBCs (stored at 4C ... diagnosis #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Fever • Bacterial ... • Subacute bacterial ... , Vasculitis (e.g ... ., PAN) • Seizures ... differential #diagnosis #rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
FNHTR once had ... very rare), or bacterial ... • Bacterial contamination ... RBCs (stored at 4C ... diagnosis #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... Fibrin degradation products ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Spontaneous Bacterial Peritonitis DIAGNOSTICS Paracentesis: • Calculate absolute PMN count (total WBC x PMN %) • Correct
Treat if other signs ... 1: 1.5 g/kg of ... ↓ rebleeding, infections ... advanced liver disease ... #prophylaxis #treatment
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... purpura: Strong sign ... Polyarteritis Nodosa: • PAN ... Thrombosis and arterial ... Differential #Diagnosis #Rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... antibody positive had ... more severe disease ... positive patients Treatment ... diagnosis #management #rheumatology
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