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diagnosis differential rheumatology anemia druginduced management sle antiphospholipid apls approach bleeding bruising comparison dermatology dil erythematosus glomerulonephritis hemostasis hepatology hypercoagulable
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Differential Diagnosis Algorithm ... Chronic Disease Normal ... #Anemia #MCV #Classification ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Idiopathic • Normal ... differential #diagnosis #algorithm ... #rheumatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... NAFLD • Others Mild ... disease US — Normal ... Others #LFTs #Hepatology ... #Causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
CRP - Usually normal ... Prognosis: Usually mild ... Discontinuation of causal ... - CRP: Usually normal ... comparison #table #rheumatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... RBC Production - Normal ... Non-lmmune #Anemia #Classification ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... deficiency - Abnormal ... Autoimmune Vasculitis (lupus ... #Causes #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... Acquired: • Mild ... discern these causes ... Differential #Diagnosis #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
sedimentation rate + Normal ... Skin Disease Classification ... Malignancy (e.g. hematologic ... CNS • Headache, mild ... vein thrombosis Hematologic
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... CRP - Usually normal ... Prognosis: Usually mild ... Discontinuation of causal ... #DIL #rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... excluded Testing: • Lupus ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
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