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diagnosis differential lupus rheumatology druginduced management anemia comparison dil erythematosus extravascular hemolysis hepatology intravascular lfts liverenzymes normocytic systemic table treatment
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Differential Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... • Early Iron Deficiency ... #Causes #Hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... • PK deficiency ... perfringens - Complement-Mediated ... #Causes #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Prognosis: Usually mild ... Discontinuation of causal ... 80% - Low complement ... comparison #table #rheumatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... NAFLD • Others Mild ... • AIH • A1AT deficiency ... disease US — Normal ... #Causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Malignancy (e.g. hematologic ... disease • Prolidase deficiency ... CNS • Headache, mild ... RNP antibodies, Complement
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... CRP - Usually normal ... 90% - Low complement ... Prognosis: Usually mild ... Discontinuation of causal
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