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diagnosis hepatology management rheumatology algorithm liver causes classification leukemia lfts abnormal agglutinin aplastic apml arthritis atlas autoimmune biliary cancer chemistry
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary Cirrhosis ... Signs and Symptoms ... bile ducts Differential ... #diagnosis #workup ... #hepatology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... Malignant tumors, Acute ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... for workup, including ... , deficiency anemia ... Kawasaki, Nephrotic syndrome ... Thrombocytosis #Platelets #Differential
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... significant portal HTN Signs ... and hepatorenal syndrome ... • Budd Chiari syndrome ... /acute hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... vein: Budd-chiari syndrome ... Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... hepatitis: < 1 • Cirrhosis
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... Leukostasis: • WBC ... Hyperuricemia • Acute ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... pylori test (GI symptoms ... changes), high MCV anemia ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - ACS, AKI, acute ... >100k, + lab signs ... diagnosis #management #hematology
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