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diagnosis differential management algorithm chronic lymphocytic mds myelodysplastic rheumatology syndrome treatment aplastic arthritis bandemia causes cbc cell classification dermatology disease
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Consider stem cell ... progress to MDS or acute ... leukemia • Associated ... management #treatment #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... 5) Symptoms of anemia ... marrow failure with anemia ... uw_IMresidency #CLL ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Management #treatment #hematology ... #oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (MCV): Average RBC ... High in acute blood ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup ... #hematology #testing
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... changes), high MCV anemia ... not required in all ... #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... Tissue damage • Leukemia ... especially in the setting ... #CBC #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Leukemia • Idiopathic ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
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