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diagnosis hematology differential lymphocytic mds rheumatology syndrome arthritis bandemia cbc chronic dermatology disease erythematosus gap globulin hemepath laboratory largegranular lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... ALL (Acute Lymphoblastic ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... treatment #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... Workup: • Complete ... diagnosis #hematology #oncology
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia Clinical - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
lymphocytosis (2-20k) with proven ... usually in the setting ... Neutropenia (85%), anemia ... as pancytopenic/ill ... presentation (PB
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Tissue damage • Leukemia ... especially in the setting ... 67% for culture proven ... 48% for culture proven ... 82% for culture proven
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for All ... the presence of anemia ... Screening Tests for Acute ... Arthritis #laboratory #workup
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Episcleritis Signs ... general feeling of ill ... - CBC may also ... #dermatology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... leukemia • Solitary ... Viral infections (acute ... anemia • Other ... inflammation (acute
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Pleural effusions • Acute ... pancreatitis, protein-losing ... lymphopenia, low PLT • Anemia ... Hodgkin lymphoma and leukemia
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