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diagnosis treatment differential syndrome leukemia renal rheumatology chronic classification cll disorders lymphocytic symptoms workup algorithm als amyotrophic antibody aplastic arteritis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... old, ~10,000 new cases ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology ... #diagnosis #management
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... of breath • Neurologic ... Leukostasis: • WBC ... Constipation • Nausea ... Hyponatremia • Nausea
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... hematuria • Signs ... hematuria: - RBC ... - Dysmorphic RBC ... #urology #nephrology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Generalized Seizures and Pseudoseizures Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
general seizure caused ... and metabolic causes ... sedative drugs, uremia ... Classification #Diagnosis #Neurology ... #Signs #Symptoms
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
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