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diagnosis hematology differential management algorithm crisis extravascular intravascular leukemia neurology oncology symptoms atlas barre chronic cll dermatology features fever gap
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Normal RBCs • Acute ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... anemia): ... uremic syndrome ... • Intrinsic RBC ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... elliptocytosis - RBC ... anemia • ... Acute HTR - Mechanical ... #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... spherocytosis, Hemolytic ... Malignant tumors, Acute ... uremic syndrome ... #differential #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute ... malignancies • Anemia ... iron deficiency, hemolysis ... Myelodysplastic syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... count cause hyperviscosity ... - ACS, AKI, acute ... >100k, + lab signs ... : • Pathophysiology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
Serum PO4 -> decr RBC ... -DPG -> - hemolysis ... - anemia ... #diagnosis #pathophysiology ... #symptoms #signs
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... Kasabach-Merritt syndrome ... - APLS • Acute ... #rheumatology #
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Crises can be precipitated ... The underlying pathophysiology ... 2) Aplasia - Acute ... of the baseline anaemia ... Crisis #Features #Signs
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
- Summary Acute ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... - NORMAL CSF WBC ... variants: (1) acute
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