15 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... disease - If ALP ... both are normal, ALP ... ALP: Bone, first ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
phos/ULN ALP) ... specificity to elevated ALP ... GGT/5-NT: ↑ • ALP ... (hemolysis) • ... #differential #Hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... Diagnosis Algorithm ALP ... - Increased ALP ... Intestine - Other causes ... biliary Cholangitis (PBC
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
of Pregnancy (AFLP ... defects. 1) HELLP (Hemolysis ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... obstruction • ALP ... or higher • Liver ... cholangitis #diagnosis #workup ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... , Elevated Liver ... child * Severe cases ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
in 1923 Low ALP ... synthesized in: liver ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
(RBC = red blood ... serum level for all ... Hemorrhage or hemolysis ... the most likely cause ... recovery also causes