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neurology syndrome treatment differential algorithm complications evaluation sclerosis 21hydroxylasedeficiency 21ohd adhesivecapsulitis agammaglobulinemia alzheimersdisease amyotrophic arthritis ascorbicacid atopic atopy bakerscyst biliary
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... chromosome 21) Signs ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management Caused by: Tropheryma whipplei Symptoms and Signs: 1. Migratory poly/oligoarthralgia
Whipple Disease ... and Management ... Caused by: Tropheryma ... whipplei Symptoms ... and Signs: 1.
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
• Myopathy (Also ... caused by hydroxychloroquine ... Erythematosus #SLE #MSK ... #signs #symptoms ... #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... should be done in ALL
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms ... #signs
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski) Brudzinski's sign is characterized
Passive neck flexion causes ... While the pathophysiology ... despite severe disease ... #PhysicalExam #Pediatrics ... #Peds
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 21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... • This is also ... Signs/Symptoms/Complications ... endocrinology #peds ... #pediatrics
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... #diagnosis #management
RADIAL HEAD FRACTURE Radial head fractures are the most common elbow fracture in adults and are
adults and are also ... fracture in adults, also ... anterior sail sign ... Radiology #XRay #Diagnosis ... #MSK
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... and Symptoms: ... disease progresses
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