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diagnosis hematology apml cancer cyp3a4 differentiation doac dyspnea inhibitors interactions malignancy management pglycoprotein syndrome
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
interactions) Cancer-treatment ... #inhibitors #Chemotherapy ... #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion
metastases Treatment ... Related: - Chemotherapy ... - Radiation induced ... #differential # ... diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... endothelial damage • Induce ... initiation • Differential ... fluid overload, PCC ... #oncology
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