15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Highest • Bone • Liver ... Intestine - Other causes ... #Algorithm #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
) - Causes of Hepatocellular ... phosphatase + ULN ... alkaline phosphatase ... Transaminitis #diagnosis ... #differential #hepatology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... Most cases diagnosed ... collection with EDTA Pathophysiology ... : • Other causes ... #hepatology #diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
, Alkaline Phosphatase ... Alkaline phosphatase ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential Diagnosis ... increase in AST/ALT ... with alkaline phosphatase ... increase in alkaline phosphate ... #hepatology #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... #differential #diagnosis ... #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
) Pathophysiology ... = nonspecific (nausea ... ) Differential Diagnosis ... Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... Algorithm Severe ... Others #LFTs #Hepatology ... #Algorithm #Causes
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... Areas of diagnostic ... ALP, alkaline phosphatase ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... : • Alkaline phosphatase ... obstruction • ALP ... #workup #hepatology