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management neurology treatment acromegaly agraphia alexia algorithm anemia antiphospholipid aplastic apls apml bcnie bloodculture cerebritis chronic cirrhosis classification cll cns
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... fluid overload, PCC ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... and Workup: • ... or refractory cases
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Out Secondary Causes ... Workup: • Complete ... #diagnosis #hematology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... but important causes ... BCNIE Diagnostic ... antiphospholipid syndrome ... #differential #workup
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Alexia Without Agraphia Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... the most common cause ... Pathophysiology: ... PCA Infarct (most ... #neurology #diagnosis
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
(SPS) - Diagnosis ... Prevalence: 1-2 cases ... Pathophysiology ... Clinical Manifestations ... antibody that works
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
Pathogenesis and Clinical ... nephrotic/nephritic syndrome ... arthritis (especially knees ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
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