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syndrome algorithm differential treatment disorders mds myelodysplastic acromegaly anemia antinxp2 antinxp2dm aplastic apml biliary bullous cholangitis chronic cirrhosis classification cll
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... of Sickle Cell Crises ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... old, ~10,000 new cases ... acute leukemia Management ... #Management #treatment ... #hematology #oncology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #Management #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... fluid overload, PCC ... #management #hematology ... #oncology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
- Differential Diagnosis ... scale on elbows & knees ... Auspitz sign, Koebner's ... Papulosquamous #SkinRash #dermatology ... #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... phenomenon CLL Diagnosis ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... Differential Diagnosis ... #workup #hepatology
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