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syndrome bullous chronic cll dermatology differentiation disorders hemeonc hemophagocytic hlh hodgkins leukemia leukostasis lymphocytic lymphohistiocytosis lymphoma lymphoproliferative lysis pemphigoid post
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... ATRA treatment Pathophysiology ... fluid overload, PCC ... #diagnosis #management ... #hematology #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology ... #diagnosis #management
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Bullous Pemphigoid - Diagnosis ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #Management #dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... phenomenon CLL Diagnosis ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... lymph node biopsy (diagnostic ... #classification ... #hematology #oncology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome caused ... Presentation • Common Signs ... Pathophysiology ... #Management #Hematology
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