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management vasculitis apml chronic cll dermatology differential differentiation disorders henochscholeinpurpura hsp iga leukemia leukostasis lymphocytic lymphoproliferative lysis post ptld rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... fluid overload, PCC ... #management #hematology ... #oncology
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
symptoms, unexplained hematologic ... EBV viral load, signs ... and classification ... to 50% of PTLD cases ... Lymphoproliferative #Disorders #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology ... #hematology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
periumbilical region), nausea ... nephrotic/nephritic syndrome ... arthritis (especially knees ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... purpura: strong sign ... #rheumatology # ... classification
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