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diagnosis treatment causes evaluation latenttb syndrome tuberculosis abscess apml betadglucan brain cd4 cns differentiation falsepositives fungal galactomannan hematology hivaids immune
Pulmonary Infections in HIV-AIDS Bacterial: • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... • CD4 < 200: PCP ... failure, COPD, Lung ... Fungal, AFB), TB ... PCR sputum, PCP
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection • Pulmonary ... Active TB: • ... staining, NAA (PCR ... #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection • Pulmonary ... Active TB: • ... staining, NAA (PCR ... #Diagnosis #Management
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent Multiple Ring-Enhancing Lesions: • Toxoplasmosis (CD4 < 100) • Other
toxo IgG • CNS PCR ... lesions • 80% with lung ... including: M, avium, TB ... multiple lesions Infectious ... Lesions #Brain #differential
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Clindamycin in case of PCN ... westermani • Other: TB ... #Abscess #pulmonary ... #differential #
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... organ dysfuxtion, ICU ... fluid overload, PCC
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
leukoencephalopathy (PML ... Leishmaniasis Differential ... • Persistently active ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Skin exam for infection ... one post op Cardiology ... Recent PCI/stenting ... since elective PCI ... unless prior heart/lung
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Other +s: PCP, Histo ... surfaces, Albumin, Infections ... in BAL does not differentiate ... concurrent admin mold-active ... result in + as long
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