8 results
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
• CD4 < 200: PCP ... failure, COPD, Lung ... , AFB), TB PCR sputum ... , PCP DFA sputum ... diagnosis #evaluation #differential
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Clindamycin in case of PCN ... Prevotella • Fungal ... Abscess Differential ... #Abscess #pulmonary ... #differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... organ dysfuxtion, ICU ... fluid overload, PCC ... APML #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection (NTM) • Fungal ... • Progressive lung ... staining, NAA (PCR ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... infection (NTM) • Fungal ... • Progressive lung ... staining, NAA (PCR ... TB #Diagnosis #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... Pseudomonas FUNGAL ... Infections #HIV #AIDS #pulmonary ... #differential # ... diagnosis #infectiousdiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... Other +s: PCP, Histo ... in BAL does not differentiate ... result in + as long ... Penicillium), Frozen ice-pops
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
transplantation • MCC ... change in the lungs ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases ... #Management #Infections