14 results
Modified penicillin binding proteins as mechanism of resistance to antibiotics.
Penicillin Binding Proteins (Transpeptidases) cross link peptidoglycan
like PCN and cephalosporins ... bind PBPS active ... the PBPS so that PCN ... again remains active ... Proteins #AMR #PBP #pharmacology
Antibiotic Classification by Mechanism of Action

Cell Wall Synthesis: 
Penicillins 
Cephalosporins 
Carbapenems 
Monobactams 
Beta-lactamase inhibitors
Glycopeptides 

 Protein
Antibiotic Classification ... by Mechanism of Action ... Penicillins Cephalosporins ... #Classification ... #Pharmacology #
Cross-Reactivity of Penicillins and Cephalosporins

Cross reactivity of penicillin-allergic patients to cephalosporins has more to do with
Penicillins and Cephalosporins ... #Penicillins #Cephalosporins ... Management #Carbapenem #Reaction ... #Incidence #PCN ... #Pharmacology
Cephalosporins 
Cephalosporins are bactericidal beta-lactam antibiotics derived from the fungus Acremonlum— they disrupt peptidoglycan formation in
predominantly active ... progressively more active ... #Generations #Classification ... #pharmacology # ... Antibiotics
Antibiotic classification refers to the categorization of antibiotics based on their chemical structure, mechanism of action,
Antibiotic classification ... , mechanism of action ... include penicillins, cephalosporins ... #Antibiotics #pharmacology ... #classification
Penicillins Antibiotics Class Overview
1. Penicillin G (IV) or V (PO)
2. Aminopenicillins - Ampicillin (IV), Amoxicillin (PO)
Penicillins Antibiotics ... Anti-pseudomonal PCNs ... Ticarcillin #Pharmacology ... #Review #Overview ... #Penicillins #PCN
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
ANTIBIOTICS WITH ... Combined PCN/Beta-Lactamase ... 2nd Generation Cephalosporins ... #Pharmacology #Antibiotics ... #Review #Overview
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... purposes including PCP ... infections in PCN-allergic ... #Pharmacology #Antibiotics ... #Review #Overview
Clindamycin - Antibiotics Class Overview
-50 S inhibitor (PO and IV)
Spectrum: Excellent activity vs. Anaerobes and Gram
Clindamycin - Antibiotics ... has activity vs PCP ... pyrimethamine) #Pharmacology ... #Antibiotics #Review
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... (Bactrim, PCN G-K ... offending medications (review ... (10g PO tid) - caution ... Treatment #potassium #nephrology