39 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
Chorioretinitis • Diagnosis ... Compatible syndrome + MRI ... toxo IgG • CNS PCR ... including: M, avium, TB ... #causes #radiology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... Clinical Signs ... decreased reflexes Pathophysiology ... : - MRI is modality ... damage - CXR should
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... negative, MOG-IgG test ... should be ordered ... , Hep A/B/CMV, TB
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... • LTBI is diagnosed ... result with no clinical ... intermediate risk of disease ... used to exclude pulmonary
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Chronic inflammation causes ... Most Common Causes ... Connective tissue diseases ... : TB, NTM, PNA ... , in advanced disease
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
PCR and CMV pp65 ... antigenemia test ... Retinitis (Most common cause ... Pancreatitis • Pulmonary ... association with PJP/TB
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Differential Diagnosis ... Debate if this should ... intersitial space Infection ... Amy Chung, MD, MSc
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based ... on clinical presentation ... Imaging: - MRI ... Demyelinating disease ... caused by the JC