13 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hemoglobinuria (PCH ... Test: Donath-Landsteiner ... test #cold # ... agglutinin #disease ... hemolytic #anemia #hematology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
- Differential Diagnosis ... Table Warm AIHA ... hemoglobinuria) • Cold Agglutinin ... Disease Mixed-type ... #Table #hematology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
( +/- ) Cold agglutinin ... disease • DAT ... #antiglobulin #test ... Autoimmune #Hemolysis #hematology ... #diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... , Drugs, Liver Disease ... Laboratory Tests ... #hematology
Dix-Hallpike Maneuver for BPPV

Procedure:
1. Make the patient sit on examination table, such that the shoulders would
Dix-Hallpike Maneuver for BPPV ... such that the shoulders ... 45° towards the test ... #Instructions #Diagnosis ... #neurology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... (CVID, WAS), (neurologic ... Causes #Workup #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... should be obtained ... (to support a diagnosis ... laboratory #workup #diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... patients with kidney disease ... patches on back, shoulder ... #comparison #table ... #dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... cascade is intact - test ... of factor VII should ... liver function tests ... #Hematology