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differential management arthritis dermatology algorithm causes comparison oncology signs symptoms workup pathophysiology clinical erythematosus lupus systemic treatment antibodies antinuclear autoantibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ANA ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... Antiphospholipid-antibody syndrome ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
ANA - Non-specific ... Anti-Scl-70 - Scleroderma ... La) - Sjogren's syndrome ... #diagnosis #table ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... Paget disease) ... #Pain #MSK #rheumatology ... #differential #diagnosis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... ), RA, crystal disease ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
and these should ... neurology, back pain ... Rheumatology ... discrepancy, multiple joint ... Peds #Pediatrics #Diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... XR, MRI to dx and ... #diagnosis #causes ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... blockers had the best ... skin disease. ... #Rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Joint Disease ... nociceptors -> Pain ... (CRP, ESR, RF, ANA ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... of Lumbar Spine and ... arthritis - (Reiter’s syndrome ... Erythematosus (SLE), should ... #Disorders #msk
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