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differential management comparison disease dermatology signs syndrome msk sle workup approach cold cppd erythematosus myopathy myositis rheumatoid systemic vasculitis activation
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... lesions • Discoid lupus ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... both at rest and ... improves quickly with rest ... #Pain #MSK #rheumatology ... #differential #diagnosis
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... hands/feet, knees, shoulders ... Signs & Symptoms ... pain / swelling ... #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... #differential #diagnosis ... #comparison #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis ... axial (spine, shoulders ... constitutional symptoms ... Joint #pain #Differential ... #rheumatology #
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... should be obtained ... , and low back pain ... #testing #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... : • Joint pain ... arthropathy • 90% joints ... : • Symptoms limited ... #Rheumatology
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