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Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... HCO3 12:10 • Respiratory ... Acidosis (pCO2 ... HCO3 7:10 • Respiratory ... Alkalosis (pCO2
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
Acid Base Compensation ... variables (pH, HCO2 ... , pCO2) move in ... it is a primary respiratory ... Alkalosis #Metabolic #Respiratory
Acid-Base Disorders - Expected Compensation Equations Metabolic Acidosis: • pCO2 = 1.5 x HCO3 + 8 ±
Acid-Base Disorders ... ↑ 0.7 Respiratory ... ∆ HCO3 ↑ 3 Respiratory ... ∆ HCO3 ↓ 4 #Acid ... Compensation #Metabolic #Respiratory
Oxygen-Hemoglobin Dissociation Curve Left Shift (↓ O2 unloading to tissue), Left = Lower: • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 • ... pathophysiology #pulmonary #respiratory
Acid Base Disorders Worksheet Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... CI-, HCO3-, PH, pCO2 ... patient's alkalosis is respiratory ... patient's acidosis is respiratory ... joshsteinbergMD #Acid
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
Acid Base and Blood ... 2. pCO2 - What’s ... the pCO2? ... Respiratory Acidosis ... production Respiratory
Blood Gas (ABG) Interpretation and Acid-Base Pathology 1- Does the patient have an acidosis or an alkalosis?
Interpretation and Acid-Base ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... calculate the expected pCO2
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis 1) Start with the Anion Gap (AG). 2)
Approach to Acid ... Generally, for acid ... and ~5 mmHg to pCO2 ... retention • Respiratory ... Ventilation • Respiratory
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... 7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... ABG #bloodgas #Acid
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
Osmolar Gap ACID-BASE ... H_def 0 mEq Acid ... )+9 Respiratory ... Respiratory Alkalosis ... )/HCO3 Acid base
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