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diagnosis causes pathophysiology spinalcord syndromes algorithm baby beriberi cauda caudaequina cord deficiency disorders equina floppy injury korsakoff management manifestations myasthenia
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
injury, often from vascular ... bladder and rectal reflex ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... aspiration and acute ... diagnosis #management #neurology
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Demyelinating Disease (MS ... , Myasthenia Gravis ... #Causes #differential ... #diagnosis #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Impairment: • Acute ... Postsynaptic: Myasthenia Gravis ... Lack of UMN/LMN signs ... #Differential #
Floppy Baby Syndrome • Infantile Botulism • Acute Flaccid Myelitis • Guillain Barre • Neonatal Myasthenia
Infantile Botulism • Acute ... Neonatal Myasthenia Gravis ... resistance - Weakness ... LMN signs - Assess ... tone, resistance, reflexes
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine • MCC- acute ... lumbar stenosis • Vascular ... lower extremity weakness ... #differential # ... diagnosis #causes #neurology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations Causes of Thiamine Deficiency: • Poor intake: - Diets
Thiamine Deficiency - Differential ... rice/processed grains ... impairments - Impaired reflexes ... extremities - Muscle weakness ... AV shunt, renal vascular
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
• Symptoms and signs ... Vascular/Blockage ... MCTD, Sjogren syndrome ... dysfunction • Abnormal reflexes ... disorders #diagnosis #neurology
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