27 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Matthew Ho, MD PhD
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing in Hemolytic ... Extravascular Hemolysis ... bilirubin LDH Peripheral ... smear Haptoglobin ... Testing #workup #diagnosis
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
Babesia spp. on Peripheral ... Blood Smear Microscopy ... parasitemia Rich Davis, PhD ... #microbiology #peripheral ... #blood #smear
Plasmodium Falciparum Gametocytes on Blood Smear.

Banana-shaped gametocytes are only seen in Plasmodium falciparum but rare in
Gametocytes on Blood Smear ... rare in blood smears ... Rich Davis, PhD, ... #peripheral #clinical ... #microscopy #microbiology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... EricsMedicalLectures/ #Peripheral ... #Blood #Smear # ... Analysis #hematology #microscopy
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... (black arrow) Peripheral ... smear changes are ... #Microscopy
A normal peripheral blood smear indicates the appropriate appearance of red blood cells, with a zone
A normal peripheral ... blood smear indicates ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Matthew Ho, MD PhD
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... #Clinical #Path ... #Microscopy #PeripheralBloodSmear
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... rare in blood smears ... Rich Davis, PhD, ... #peripheral #clinical ... #microscopy #microbiology