11 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... Infection (sepsis), PE ... #APML #diagnosis
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Myeloid Leukemia (AML ... 🔬Tumor cells are ... size lymphoid cells ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... involve one, two, or all ... transformation to AML ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse
bullous lesions (not shown). These
of leukemic cells ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology ... Leukemic #Infiltrate #AML
A quick infographic on the importance of sun protection and the various results of sun damage
causes #diagnosis #dermatology ... Toxicol Appl Pharmacol ... non-melanoma skin cancer: clinical ... Kuriger JK, et al ... damage in skin cells