49 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Infection (sepsis), PE ... #APML #diagnosis ... #management #hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... #differential #diagnosis ... #dermatology #nails
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... #differential #diagnosis ... #dermatology #nails
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Differential Diagnosis ... Vasculature: - PE ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... #differential #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... • Clinically ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
Pulmonary Pathology ... Respiratory Distress Syndrome ... Pulmonary Embolism (PE ... massive/submassive PE ... #differential #diagnosis