12 results
Beta Blocker Side Effects / Toxicity
Cardiac Side Effects:
 • Sinus bradycardia, AV block, Heart failure exacerbation,
Side Effects / Toxicity ... anxiety, increased risk ... #SideEffects #Toxicity ... AdverseEffects #pharmacology
Debridement and Management of Prosthetic Joint Infection (PJI)
Duration of symptoms <3 weeks OR  <30 days
Joint Infection (PJI ... whether benefit > risk ... Cortes_Penfield #PJI
Summary of the adverse effects associated with the use of trimethoprim–sulfamethoxazole

Mnemonic - NOT RISKY?

N - Neurologic
Mnemonic - NOT RISKY ... - Reproductive toxicity ... #SideEffects #Pharmacology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Increases bleeding risk ... increased bleed risk ... of digoxin toxicity ... for toxicity • ... supplementals #herbal #pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
- increased risk ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
Therapy after PCI ... - Bleeding risk ... reduced bleeding risk ... anticoagulation #PCI ... #pharmacology #
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Bipolar Disorder Toxicity ... , weight gain Toxicity ... patients are at risk ... for lithium toxicity ... #Pharmacology #
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
an independent risk ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology
Methadone in Hospice & Palliative Care
Appropriate Candidates:
 - Moderate to severe pain
 - Pain refractory to
misuse - Multiple risk ... for methadone toxicty ... prolongation or at high risk ... PalliativeCare #Pharmacology
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
due to potential toxicity ... often outweighs risk ... appropriate patients) - Toxicity ... #Pharmacology #Antibiotics