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diagnosis hematology cryofibrinogenemia differential hemeonc hemophagocytic hlh hus lymphohistiocytosis management microangiopathy monoclonal oncology paraproteinemias scleroderma sclerosis signs ssc symptoms testing
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
There are primary ... and secondary TMA ... Primary TMA is due ... catastrophic APS, SRC ... #hematology #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
of Scleroderma (SSc ... Hepatic: PBC (primary ... pulmonary arterial HTN ... renal crisis (SRC ... #rheumatology #
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... processes: • Systemic ... Warfarin-induced skin ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... nephropathy • TMA ... thrombosis+Pulm HTN ... +skin) • Scleromyxedema ... Paraproteinemias #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... Types of HLH • Primary ... STX11, STXBP2 • Secondary ... (often termed MAS-HLH ... Diagnosis #Management #Hematology
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