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diagnosis management rheumatology blood differential product purpura reactions algorithm cryofibrinogenemia microangiopathy monoclonal morphology nonpalpable oncology palpable paraproteinemias skinlesion thrombocytopenic tmas
Treatment of Thrombotic Thrombocytopenic Purpura (TTP) Diagnosis of TTP: • Rare and severe, ADAMTS13 deficiency • Autoimmune
Treatment of Thrombotic ... condition (vs. secondary ... HUS), Serum creatinine ... HUS) Treatment ... #hematology
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... are primary and secondary ... catastrophic APS, SRC ... pregnancy, & malignant HTN ... Microangiopathy #TMAs #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... leakage of RBC's secondary ... /HUS - Hemolytic ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
necrosis) - Thrombosis ... (Thrombotic vasculopathy ... Cryoglobulinemia • TTP ... , HUS and HIT ... #hematology
Morphology of Secondary Skin Lesions - Description Algorithm Secondary Skin Lesion - Lesion that develops from trauma,
Description Algorithm ... Secondary Skin ... serum, blood, or pus ... #Description #Algorithm ... #dermatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Organomegaly+↑RBC/plt+, ↑thrombosis ... +Pulm HTN+skin) ... Hyperviscosity (Thrombosis ... Paraproteinemias #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Transfusion Purpura (PTP ... Occurs between 0-6 hrs ... infections with skin ... RBCs (stored at 4C ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusion Purpura (PTP ... Occurs between 0-6 hrs ... infections with skin ... RBCs (stored at 4C ... diagnosis #management #hematology
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