13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
HELLP Syndrome and Acute ... child * Severe cases ... #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... TTPHUS #HELLP #AFLP ... #Obstetrics #OBGyn ... #Hematology #Diagnosis ... #Comparison #Table
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... = nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... #hepatology #obstetrics
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... - Drugs - Pregnancy ... #Algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... melanoma, myeloma • Pregnancy ... #algorithm #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... (AFLP) • Onset ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Algorithm Severe ... • Wilson's • Pregnancy ... - AFLP, HELLP ... Bile Ducts • PSC ... #Algorithm #Causes
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... - Differential Diagnosis ... Toxic: Medication, Pregnancy ... #Causes #Acute ... #algorithm #hepatology
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
- Differential Diagnosis ... heart failure, acute ... findings based on cause ... #table #comparison ... #criticalcare
Approach to Possible Hypertensive Emergency

criteria required to diagnose hypertensive emergency
(1) Severe hypertension
 - Usually a MAP
mm is needed to cause ... patients who have acute ... hypertension (e.g. pregnant ... , such as: - Acute ... #Algorithm #CriticalCare