9 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
TTP/HUS, HELLP Syndrome ... of Pregnancy (AFLP ... ) Three syndromes ... child * Severe cases ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #Diagnosis #Comparison ... #Table
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... Pathophysiology: • Defect ... , ↑Tbili/Dbili/AP ... infiltration) Differential ... Liver #Pregnancy #hepatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... Grey Platelet Syndrome ... #comparison #table ... #differential # ... diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... Vascular Causes ... vein: Budd-chiari syndrome ... #hepatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Kasabach-Merritt syndrome ... vasculitis - GPA ... #Diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Causes of Monoclonal ... changes (POEMS syndrome ... gastric tumors • Hematology ... #ProteinGap #differential ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Paraneoplastic effects ... life-threatening Differential ... myasthenia Diagnosis ... immunologic assay - MuSK ... Myasthenia #Gravis #diagnosis