12 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... , fever, joint pain ... + distinctive primary ... #Hematology #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... Non-Hodgkin's Lymphoma ... Reed-Sternberg Cells ... • Hodgkin's Lymphoma ... #Hematology #Oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Alcohol-induced pain ... : Pain in involved ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... obstruction • ALP ... bile ducts Differential ... Endocrinopathy, Lymphoma ... cholangitis #diagnosis #workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... not required in all ... unclear, or if a primary ... #Workup #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... hemolytic anemia • Pain ... Workup: • Full ... Immunohistochemical studies (to differentiate ... #oncology #management
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... dysfunction • PSC ... infarction • Lymphoma ... Ovarian CA Diffuse ... #Differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... • Induce blast cell ... initiation • Differential ... fluid overload, PCC ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... involve one, two, or all ... Workup: • Complete ... blood count with differential ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... myeloma • Plasma cell ... : Lymphoma, Leukemia ... Gap #ProteinGap #differential