19 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... Bone symptoms - Pain ... - Drugs - Primary ... #Elevation #Differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Alcohol-induced pain ... : Pain in involved ... - Pruritus: (focal ... NonHodgkins #comparison #oncology ... #hematology
Ear Pain (Otalgia) - Differential Diagnosis Framework

Primary Otalgia 
 - Pain that originates from the ear
) - Differential ... Basal/squamous cell ... the tragus to differentiate ... #Otology #Otolaryngology ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... not required in all ... unclear, or if a primary ... Platelet #Disorders #Differential ... #Workup #hematology
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Malignancy (e.g. small cell ... SSRIs) Severe pain ... renal failure - Primary ... #Diagnosis #Table ... #Causes #Sodium
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... Skin changes • Urinary ... dysfunction • PSC ... intolerance • SIBO Focal ... #Differential #
Primary and Secondary Headaches - Red Flags and Differential Diagnosis
Red Flags (SNOOP):
S - Systemic		
N - Neurologic
Primary and Secondary ... Red Flags and Differential ... Pallor, Sweating, Focal ... Thrombosis, Giant Cell ... #causes #primary
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... • Induce blast cell ... initiation • Differential ... fluid overload, PCC ... #oncology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Abnormalities in primary ... lesions • Severe pain ... #dermatology #physicalexam