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hematology oncology treatment acromegaly aflp apml biliary causes cholangitis cirrhosis classification coagulation dic differentiation disseminated encephalopathy endocrinology fatty gap globulin
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Diagnosis: • ... bile ducts Differential ... Diagnosis: • ... #workup #hepatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
and Management ... (at injection sites ... ♀, ↑Age, ESRD Pathophysiology ... heparin-PF4 complex → plt ... #Hematology #HemeOnc
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... or venipuncture sites ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... Differential Diagnosis ... Beckwith Wiedemann syndrome ... and Workup: • ... #Treatment #Pathophysiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Reversible course Differential ... Diagnosis: • ... Seizures: Treat with AEDs ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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