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differential hematology leukemia management nephrology acute aki algorithm apml chronic classification cll differentiation emergencies encephalopathy hyponatremia injury kidney lymphocytic oncologic
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... renal failure • Hypocalcemia ... #differential #diagnosis ... #cancer
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Patients with Cancer ... Cancer Related ... #Oncology #Differential ... #Diagnosis #Classification ... #Nephrology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... : >3 symptoms, or ... fluid overload, PCC ... management #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... lymphoid organs When Cancer ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... with no early symptoms ... phenomenon CLL Diagnosis ... • Richter’s Syndrome ... #workup #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Autoimmune disease, Cancer ... Etiology: • Pathophysiology ... Neurological symptoms ... #neurology
Hyponatremia Differential Diagnosis Algorithm in Cancer UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Hyponatremia Differential Diagnosis ... Algorithm in Cancer ... appropriate • Hypovolemia ... capillary leak syndrome ... #nephrology #oncology
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