16 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Diagnosis and Management ... Lymphoproliferative disorders ... Syndrome #Diagnosis #Management ... #treatment #hematology ... #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... glucocorticoid treatment ... symptoms (eg, skin ... #Algorithm #Differential ... #diagnosis #hematology
Severe Drug Rashes - Comparison - DRESS | SJS/TEN | AGEP | Erythroderma

DRESS 
 - Onset:
Drug Rashes - Comparison ... >90% of total skin ... #TABLE #DRESS # ... #Erythroderma #Dermatology ... #Emergency #Differential
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
arterial thrombosis, skin ... heparin-PF4 complex → plt ... hypercoagulable state and plt ... exposure (prevent skin ... #Treatment #Hematology
Scleroderma Like Conditions - Differential Diagnosis
Eosinophilic Fasciitis:
 - Orange peel induration (peau d'orange) of proximal extremities
Like Conditions - Differential ... the mainstay of treatment ... #Scleroderma #Differential ... #Diagnosis #comparison ... #table #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Skin involvement ... Resolution > 15 days Differentials ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
chronic inflammatory disorder ... Autoinflammatory disorder ... and lower jaw Treatment ... #diagnosis #management ... #Dermatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology