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algorithm causes hematology lfts liver syndrome aflp apml cholangitis cirrhosis coagulation dic differentiation disseminated elevated fatty gitelman hepatitis hypokalemia injury
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... - CBD stone, Biliary ... #hepatology #LiverFunctionTests
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... disease US — Normal ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... function may be abnormal ... #diagnosis #algorithm ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Diagnosis: Viral ... Liver #Pregnancy #hepatology ... #management #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... fluid overload, PCC ... #management #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... abnormalities - PLT ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... bouts of HTN Diagnostic ... Sjogren's • CSF: - Abnormal ... #management #neurology ... #differential
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Metabolic alkalosis • Normal ... ratio 0.5%) Differential ... Gitelman #Syndrome #diagnosis ... #nephrology #management ... #pathophysiology
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