11 results
Summary table of comparison of the difference between primary biliary cholangitis (PBC) and primary sclerosing cholangitis
Summary table of ... between primary biliary ... cholangitis (PBC ... sclerosing cholangitis (PSC ... #differential #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Tests - Differential ... Ducts - PBC ... , PSC, Alcoholic ... - CBD stone, Biliary ... stricture, PSC,
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... bile ducts Differential ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis ... function may be abnormal
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... disease US — Normal ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... (+) ↑ WBC ... Blood #Disorders #hematology ... #Markers #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
syndrome (MDS) (normal ... • ↓ WBC • ↓ ... PLT • Reticulocyte ... #oncology #hematology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
initiation • Differential ... 500 mg QD until normal ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... 1.5x ULN and/or abnormal ... survey disease #PBC ... #Primary #Biliary ... #Treatment #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Thalassemia, Sickle cell anemia ... chain assay • An abnormal ... Gap #ProteinGap #differential